MeDEISA is a medical image and signal database, proposed by the « Engineering in Medicine and Biology » (EMB) French Chapter of the IEEE, Section France. It can be used as a tool to perform objective evaluations of image and signal processing algorithms (such as coding, denoising, segmentation,…). Furthermore, it can be used to achieve method performance comparisons. Our objective consists in gathering the various acquisition modalities of Magnetic Resonance Imaging, X-rays, Echography, Scintigraphy, with various human organs, various pathologies and various degrees of subtleties.Each image, each spatial, temporal or spacio-temporal sequence is proposed in various formats (DICOM, PNG useful for compression purpose...), jointly with a descriptive text file that specifies the features of each medical image/signal. The access to MeDEISA for downloading the images/signals is totally free of charge. We made it available for scientist communities, obviously for non commercial purposes. The official website of medeisa is here.